← TRACKER

BIOTECHNOLOGY

DIMENSION BIOTECHNOLOGY · 1975 — PRESENT AI · TODAY
THE ASILOMAR MODEL
THEN

In 1975, leading biologists voluntarily paused recombinant DNA research and convened the Asilomar Conference to establish safety guidelines BEFORE accidents happened. It worked — the guidelines prevented catastrophes for decades.

NOW

The FLI Pause Letter (2023) called for a 6-month pause on frontier AI training. No lab paused. The Asilomar model failed because AI development is driven by corporate competition, not academic research. There's no grant funding to cut off.

CI FACTOR: Corporate Race
DUAL-USE DILEMMA
THEN

Same techniques that cure diseases can create bioweapons. The Biological Weapons Convention (1972) bans bioweapons but can't prevent dual-use research.

NOW

Same models that write code can write malware. Same models that assist drug discovery can design pathogens. No AI Weapons Convention exists. The dual-use problem is inherent to general-purpose AI.

CI FACTOR: Incident Frequency
GAIN-OF-FUNCTION DEBATE
THEN

Should researchers deliberately enhance pathogen capability to study defenses? Years of debate, moratoriums, and eventual regulated resumption.

NOW

Should labs deliberately push capability frontiers to study safety? The "capability research is safety research" argument mirrors "gain-of-function is defensive." Same tension, same rationalizations.

CI FACTOR: Model Capability